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Intrinsic sphincter dysfunctionView Articles
Intrinsic sphincteric deficiencyView Articles
Invasive cancerView Articles

Volume 9, Number 4Meeting Reviews

Best of the 2007 AUA Annual Meeting (2)

Meeting Review

John P Stein

Bladder Cancer Highlights from the 2007 Annual Meeting of the American Urological Association, May 19-24, 2007, Anaheim, CA [Rev Urol. 2007;9(4):220-234]

Bladder cancerQuality of lifeRisk factorsAgeCystectomyLaparoscopic surgeryIntravesical therapyPrognosisCystoscopyGenderInvasive cancerLymph node dissectionLymphovascular invasionMetastatic cancerOutcomesRepeat TURRobotic-assisted surgerySuperficial cancer

Iodine-125View Articles
IontophoresisView Articles

Volume 13, Number 3Review Articles

Peyronie’s Disease: Nonsurgical Therapy Options

Treatment Update

Franklin E KuehhasNenad DjakovicPeter WeiblTosev GeorgiRalf Herwig

Peyronie’s disease (PD) is a fibrous inelastic scar of the tunica albuginea, leading to penile deformity, penile curvature, shortening, narrowing, and painful erections that subsequently lead to painful or unsatisfying sexual intercourse. No consensus exists yet on the ideal management of PD. This fact is a result of our limited knowledge of its etiology and causative factors. The acute presentation of PD is treated conservatively, and surgical approachesare only attempted if severe curvature, narrowing, or indentation persists for more than 1 year; PD stability exists for at least 3 months; curvature impedes sexual intercourse; and severe penile shortening occurs. This review focuses on new developments for conservative treatment strategies for PD. [Rev Urol. 2011;13(3):139-146 doi: 10.3909/riu0528] © 2011 MedReviews®, LLC

Peyronie’s diseaseNonsurgical therapyOral medicationIntralesionaltherapyExtracorporeal shock wave therapyIontophoresisPenile traction systems

Irreversible electroporationView Articles

Volume 19, Number 4Case Review

Irreversible Electroporation for Prostate Cancer as Salvage Treatment Following Prior Radiation and Cryotherapy

Katie S MurrayOguz AkinJonathan A Coleman

Salvage treatment options after localized primary treatment failure of prostate cancer are limited and associated with risk for serious complications. We report on the management details of a 57-year-old African American man treated with partial-gland ablation using irreversible electroporation following local recurrence after brachytherapy and prior salvage cryoablation. Therapeutic and functional outcomes were assessed by conventional means, including serum prostate-specific antigen values and prostate biopsy results. [Rev Urol. 2017;19(4):268–272 doi: 10.3909/riu0755] © 2018 MedReviews®, LLC

Prostate cancerFocal therapyIrreversible electroporationSalvage therapy

Irritable bowel syndromeView Articles
Ischemic priapismView Articles

Volume 12, Number 1Case Review

Diagnostic and Therapeutic Options for the Management of Ischemic and Nonischemic Priapism

Case Review

Jacob RajferJeffrey Bassett

Priapism is defined as persistent penile erection continuing beyond, or unrelated to, sexual stimulation. Proper diagnosis encompasses at least 2 very different pathophysiologic processes. Ischemic priapism (“low flow”) is a disorder of venous outflow and/or stasis. Nonischemic priapism (“high flow”) is a disorder of arterial flow. We present 2 cases that review each condition. The first case highlights a 32-year-old man with a medical history of sickle cell disease who presented to the emergency department complaining of a persistent, painful erection that had continued for 18 hours. The second case describes a 24-year-old man with no significant medical history who sustained trauma to his pelvis while skateboarding. Although the initial evaluation of both types of priapism is similar, pathophysiology and resulting interventions differ for each, underscoring the importance of proper diagnosis.[Rev Urol. 2010;12(1):56-63 doi: 10.3909/riu0457]

Erectile dysfunctionIschemic priapismNonischemic priapismIntracorporeal pressureCavernosal hypoxiaPhosphodiesterase type 5Distal shunts

Joint hypermobilityView Articles
Joule-Thomson effectView Articles
Juxtaglomerular apparatus tumorView Articles
KallikreinView Articles
KetoconazoleView Articles
KidneyView Articles
Kidney and testis injuryView Articles
Kidney calculiView Articles
Kidney calculi/diet therapyView Articles
Kidney cancerView Articles
Kidney neoplasmsView Articles

Volume 23, Number 4Kidney Cancer

Imaging Techniques in the Diagnosis of Renal Cell Carcinoma: Contemporary Trends and Future Directions

Gautam Jayram

Increasing radiographic detection of incidental small renal masses has led to a growing concern regarding overtreatment of these lesions. Given the limitations of computed tomography and magnetic resonance imaging, there is an unmet need for improved kidney imaging techniques that can provide more accurate assessments of renal lesions. This review provides a summary of established kidney imaging modalities and also those likely to be meaningful in the near future. Kidney imaging has evolved, with several modalities contributing to the overall diagnostic landscape. There is great optimism that a new era of molecular imaging in renal cell carcinoma can vastly improve diagnostic capabilities and limit unnecessary invasive procedures.

Carcinoma, renal cellCarcinomaKidney neoplasmsmolecular imagingpositron-emission tomography

Kidney stonesView Articles

Volume 6, Number 3Meeting Reviews

Best of the 2004 AUA Annual Meeting

Highlights from the 2004 Annual Meeting of the American Urological Association, May 8-13, 2004

Dean G AssimosEllen ShapiroAlan W PartinMichael B ChancellorJ Curtis NickelJacob RajferClaus G RoehrbornMichael K BrawerRandall B MeachamKevin M SlawinBob DjavanArie S BelldegrunMichael P O'LearyJohn S LamStephen J FreedlandYan Kit FongTheodore AnagnostouOleg ShvartsNaveen Kella

Prostate cancerRenal cell carcinomaObesityRobotic surgeryKidney stonesLaparoscopyBenign prostatic hyperplasiaBladder cancerOncologyLower urinary tract symptomsProstate-specific antigenOveractive bladderRadical prostatectomyMale infertilityUrolithiasisErectile dysfunctionPediatric urologyChronic prostatitisIncontinenceTumor markersBasic science

Klinefelter syndromeView Articles

Volume 17, Number 1Case Review

Rare Case of Monozygotic Twins Diagnosed With Klinefelter Syndrome During Evaluation for Infertility

Edmund S SabaneghYagil Barazani

Although neither Klinefelter syndrome nor monozygotic twins are particularly rare (1/667 male births and 3-4/1000 live births, respectively), the occurrence of both in the same pregnancy (ie, identical twins with Klinefelter syndrome) is exceedingly rare and has only been reported three times previously in the literature. This report describes the fourth ever reported case of monozygotic twins with Klinefelter syndrome (who presented to our male fertility clinic with failure to conceive) and sheds interesting light on the reproductive concordance observed with this rare clinical entity. To our knowledge, this is the first reported case of monozygotic twins with Klinefelter syndrome that describes the infertility workup and outcomes of microsurgical testicular sperm extraction. [Rev Urol. 2015;17(1):42-45 doi: 10.3909/riu0628] © 2015 MedReviews®, LLC

Klinefelter syndromeMicrosurgical testicular sperm extractionAzoospermiaSertoli only syndromeGerm cell aplasia

Klinefelter’s syndromeView Articles
Krebs cycleView Articles
KTP laserView Articles

Volume 8, Supplement 3Review Articles

Expanding the Role of Photoselective Vaporization of the Prostate

Photoselective Vaporization of the Prostate

Steven A Kaplan

The use of the potassium-titanyl-phosphate (KTP) laser for the ablative treatment of lower urinary tract symptoms secondary to benign prostatic hyperplasia (BPH) has gained wide acceptance in the urologic community. The efficacy and safety of photoselective vaporization of the prostate using 60-W or 80-W KTP have been demonstrated in multiple trials, with significant impact on special high-risk surgical populations (ie, patients with large prostates and anticoagulated patients with multiple comorbidities) with symptomatic BPH. The high-power KTP laser technique has also shown encouraging results in the management of urethral strictures. With catheter removal, improvement in voiding may not immediately occur; however, with the efficient vaporization and limited coagulation necrosis that are routinely noted with high-power KTP applications, improvement may occur in as early as a few days to 1 week. Because of the superior surgical hemostasis associated with laser prostatectomy, no restrictions on physical activity are required after the procedure, even in the immediate postoperative period. [Rev Urol. 2006;8(suppl 3):S3-S8]

BPHUrethral stricturesProstatectomyKTP laserVaporization

Lap PakView Articles

Volume 14, Number 3Review Articles

Lap Pak for Abdominal Retraction

New Technology Review

Gary D SteinbergHerbert LeporGanesh SivarajanSam S ChangAmr FerganyS Bruce Malkowicz

Retraction of the bowels during abdominal surgery is generally facilitated by the use of a combination of various retractors along with surgical towels or sponges. The use of surgical towels and sponges may lead to retained foreign bodies or adhesions. In addition, these towels and sponges often require manipulation during long surgical procedures. The ideal way to avoid these problems in abdominal surgery is to develop a technique for retraction of the abdominal contents that eliminates the requirement for these foreign bodies. This article presents the results of a small trial for Lap Pak (Seguro Surgical, Columbia, MD), a disposable radio-opaque device that is made of silicone and retracts the bowels in a cephalad orientation without the need for towels or sponges. [Rev Urol. 2012;14(3/4):41-47 doi: 10.3909/riu0572] © 2013 MedReviews®, LLC

RetractionPostoperative adhesionsRetained foreign bodiesLap Pak

Laparoscopic cholecystectomyView Articles

Volume 13, Number 4Review Articles

Changing Patterns in Iatrogenic Ureteral Injuries

Treatment Review

Dean G AssimosVictoriano RomeroHaluk AkpinarJohn Smith III

Advances in laparoscopic and endoscopic surgery over the past 25 years have changed the preferred methods for performing many operations. We previously reported an increase in the number of patients treated for ureteral injury at our institution that paralleled the introduction of minimally invasive techniques. Since that report, more advanced endoscopic procedures have been introduced. We sought to determine whether the latter influenced the number of ureteral injuries managed at our institution. Reported here are the results of our retrospective study, which sought to determine if the rate of treatment of major iatrogenic ureteral injuries has changed. [Rev Urol. 2011;13(4): e179-e183 doi: 10.3909/riu0537] © 2011 MedReviews®, LLC

UreteroscopyUreteral injuryLaparoscopic cholecystectomyProximal ureterRenal salvage

Laparoscopic nephroureterectomyView Articles

Volume 19, Number 1Review Articles

Systematic Review of Open Versus Laparoscopic Versus Robot-assisted Nephroureterectomy

Systematic Review

Kamran AhmedEmma MullenBen Challacombe

Upper tract urothelial carcinoma is a relatively uncommon malignancy. The gold standard treatment for this type of neoplasm is an open radical nephroureterectomy with excision of the bladder cuff. This systematic review compares the perioperative and oncologic outcomes for the open surgical method with the alternative surgical management options of laparoscopic nephroureterectomy and robot-assisted nephroureterectomy (RANU). MEDLINE, EMBASE, PubMed, and Cochrane Library databases were searched using a sensitive search strategy. Article inclusion was then assessed by review of abstracts and full papers were read if more detail was required. In all, 50 eligible studies were identified that looked at perioperative and oncologic outcomes. The range for estimated blood loss when examining observational studies was 296 to 696 mL for open nephroureterectomy (ONU), 130 to 479 mL for laparoscopic nephroureterectomy (LNU), and 50 to 248 mL for RANU. The one randomized controlled trial identified reported estimated blood loss and length of stay results in which LNU was shown to be superior to ONU (P < .001). No statistical significance was found, however, following adjustment for confounding variables. Although statistically insignificant results were found when examining outcomes of RANU studies, they were promising and comparable with LNU and ONU with regard to oncologic outcomes. Results show that laparoscopic techniques are superior to ONU in perioperative results, and the longer-term oncologic outcomes look comparable. There is, however, a paucity of quality evidence regarding ONU, LNU, and RANU; data that address RANU outcomes are particularly scarce. As the robotic field within urology advances, it is hoped that this technique will be investigated further using gold standard research methods. [Rev Urol. 2017;19(1):32-43 doi: 10.3909/riu0691] © 2017 MedReviews®, LLC

Urothelial carcinomaRobot-assisted nephroureterectomyopen nephroureterectomyLaparoscopic nephroureterectomy

Laparoscopic partial nephrectomyView Articles

Volume 13, Number 3Review Articles

A Review of Current Hemostatic Agents and Tissue Sealants Used in Laparoscopic Partial Nephrectomy

Treatment Review

I GalanakisN VasdevN Soomro

Laparoscopic partial nephrectomy (LPN) is currently considered to be one of the most challenging procedures in minimally invasive urological surgery. With an increasing number of renal tumors being managed using LPN, there is now a further interest in the development of techniques and agents to reduce complications associated with the procedure. Hemostasis is of paramount importance during LPN, and hemostatic agents and tissue sealants are now being used commonly during LPN. Despite this, there is a dearth of prospective, randomized, human trials in current literature that compare the various agents. This review evaluates hemostatic agents and tissue sealants being used during LPN as an adjuvant to suturing in human studies. [Rev Urol. 2011;13(3):131-138 doi: 10.3909/riu0524] © 2011 MedReviews®, LLC

Laparoscopic partial nephrectomyRenal tumorsHemostatic agentsTissue sealantsSuturing adjuvant

Laparoscopic radical nephrectomyView Articles
Laparoscopic radical prostatectomyView Articles

Volume 8, Supplement 2Review Articles

New Techniques and Management Options for Localized Prostate Cancer

16th International Prostate Cancer Update

Mack Roach IIIJoycelyn L Speight

Prostate cancer is diagnosed in younger men who want treatment that does not compromise their quality of life, take time away from work, or cause worrisome side effects. Laparoscopic radical prostatectomy, robot-assisted laparoscopic radical prostatectomy, and third-generation cryotherapy are modifications of previously used techniques in the treatment of prostate cancer and are presented in this article. Although some or all of the outcomes might be expected to change in the future, the urologic surgeon is left to select an approach, presumably on the basis of the experience, level of training, and care pathways at his or her institution. [Rev Urol. 2006;8(suppl 2):S22-S29]

Prostate cancerLaparoscopic radical prostatectomyThird-generation cryotherapy