Volume 6, Supplement 8SupplementNeoadjuvant Hormonal Therapy in Men Being Treated With Radiotherapy for Localized Prostate CancerMack Roach IIIProstate cancerRadiotherapyExternal beam radiotherapyRandomized trialsNeoadjuvant hormonaltherapy
Volume 6, Supplement 4SupplementAdvances in BrachytherapyJohn SylvesterPeter GrimmProstate cancerExternal beam radiotherapyIodine-125Palladium-103Seed brachytherapyTransperineal approach
Volume 15, Number 3Review ArticlesBladder Cancer After Radiotherapy for Prostate CancerSystematic ReviewFrancesca SurianoEmanuela AltobelliFederico SergiMaurizio BuscariniExternal beam radiotherapy (EBRT) is frequently used in the management of prostate cancer (PCa) as definitive, postoperative, or salvage local treatment. Although EBRT plays a central role in the management of PCa, complications remain a troubling by-product. Several studies have demonstrated an association between radiotherapy and elevated risk of acute and late toxicities. A secondary malignancy induced by initial therapy represents one of the most serious complications related to definitive cancer treatment. The radiation-related secondary primary malignancy risk increases with increasing survival time. Transitional cell carcinoma of the bladder is the most frequent secondary primary malignancy occurring after radiotherapy and is described as more aggressive; it may be diagnosed later because some radiation oncologists believe that the hematuria that occurs after prostate EBRT is normal. Some patients treated for localized PCa will subsequently develop invasive bladder cancer requiring surgical intervention. Patients with PCa treated with EBRT should be monitored closely for the presence of bladder cancer. [Rev Urol. 2013;15(3):108-112 doi: 10.3909/riu0577] © 2013 MedReviews®, LLCProstate cancerBladder cancerRadiotherapyExternal beam radiotherapy