Volume 11, Number 2Case ReviewGenitourinary SarcoidosisEdmund S SabaneghPravin K RaoGenitourinary involvement of sarcoidosis can mimic many common urologic conditions. Although sarcoidosis is a benign inflammatory condition, it can present much like malignant or infectious conditions; thus, failed diagnosis can lead to unnecessary medications or surgical procedures. In addition, management choices for patients with scrotal findings have important implications for future fertility. Thus, this uncommon condition should be on the differential diagnosis for any urologic patient. The authors report on a patient with a scrotal mass as his presenting symptom of sarcoidosis and review the diagnosis, implications, and management of sarcoidosis involving all potential sites in the urinary tract.[Rev Urol. 2009;11(2):108-113]UrologySarcoidosisGenitourinaryScrotal mass
Volume 15, Number 4Case Review47,XYY Syndrome and Male InfertilityEdmund S SabaneghIna W KimArjun C KhadilkarEdmund Y KoMen with 47,XYY syndrome present with varying physical attributes and degrees of infertility. A retrospective chart review was performed on a male infertility and genetic anomaly database. Three patients with 47,XYY were found. Each presented with . 2 years of infertility. All were tall with elevated body mass indices. Scrotal findings ranged from normal to atrophic testicles. Semen analyses demonstrated oligospermia and varying endocrine profiles. Because of the diverse phenotype and potential lack of symptoms, identification and diagnosis of men with 47,XYY syndrome may be difficult. We recommend careful screening of 47,XYY patients and referral to primary physicians for long-term follow-up for increased incidence of health-related comorbidities. [Rev Urol. 2013;15(4):188-196 doi: 10.3909/riu0580] © 2014 MedReviews®, LLCXYY syndromeInfertility syndromes
Volume 16, Number 4Case ReviewTesticular Sclerosing Sertoli Cell Tumor: A Case Report and Review of the LiteratureEdmund S SabaneghYagil BarazaniSarah ColemanAndres A RomaSertoli cell tumors are very rare testicular tumors, representing 0.4% to 1.5% of all testicular malignancies. They are subclassified as classic, large-cell calcifying, and sclerosing Sertoli cell tumors (SSCT) based on distinct clinical features. Only 42 cases of SSCTs have been reported in the literature. We present a case of a 23-year-old man diagnosed with SSCT. [Rev Urol. 2014;16(4):191-193 doi: 10.3909/riu0620] © 2014 MedReviews®, LLCTesticular neoplasmSertoli cell tumorSclerosing Sertoli cell tumor
Volume 17, Number 1Case ReviewRare Case of Monozygotic Twins Diagnosed With Klinefelter Syndrome During Evaluation for InfertilityEdmund S SabaneghYagil BarazaniAlthough neither Klinefelter syndrome nor monozygotic twins are particularly rare (1/667 male births and 3-4/1000 live births, respectively), the occurrence of both in the same pregnancy (ie, identical twins with Klinefelter syndrome) is exceedingly rare and has only been reported three times previously in the literature. This report describes the fourth ever reported case of monozygotic twins with Klinefelter syndrome (who presented to our male fertility clinic with failure to conceive) and sheds interesting light on the reproductive concordance observed with this rare clinical entity. To our knowledge, this is the first reported case of monozygotic twins with Klinefelter syndrome that describes the infertility workup and outcomes of microsurgical testicular sperm extraction. [Rev Urol. 2015;17(1):42-45 doi: 10.3909/riu0628] © 2015 MedReviews®, LLCKlinefelter syndromeMicrosurgical testicular sperm extractionAzoospermiaSertoli only syndromeGerm cell aplasia
Volume 18, Number 1Case ReviewAdenomatoid Tumor of the Testis Arising From the Tunica AlbugineaAndrew Y SunA Scott PolackwichEdmund S SabaneghAdenomatoid tumors are the most common paratesticular tumor. Although they primarily arise from the epididymis, they can rarely occur as an isolated intratesticular mass. These tumors are benign and surgical excision is curative. We present a case of a 36-year-old man diagnosed with an intratesticular adenomatoid tumor. [Rev Urol. 2016;18(1):51-53 doi: 10.3909.riu0690] © 2016 MedReviews®, LLCTesticular neoplasmAdenomatoid tumor