Volume 23, Number 4Prostate CancerDeep Learning for Magnetic Resonance Imaging–Based Radiation Therapy for Prostate Cancer: Current StatusJessica E. ScholeyAbhejit RajagopalJulian HongPeder LarsonKe ShengMagnetic resonance imaging (MRI) is increasingly being used for external beam radiation therapy in the treatment of prostate cancer because of its excellent soft tissue contrast and ability to provide functional and physiologic information about tumor behavior. At the same time, deep learning has seen widespread applications in medical imaging, including for MRI-based classification and synthesis. Deep learning–based approaches are being incorporated into the MRI-guided clinical external beam radiation therapy workflow for patient simulation, contouring of targets and critical structures, treatment planning, and treatment delivery. In this review, we examine the current status of deep learning for MRI-guided prostate external beam radiation therapy.Artificial intelligenceProstatic neoplasmsRadiotherapyMagnetic resonance imaging (MRI)Deep Learning
Volume 23, Number 1Prostate CancerContemporary Approaches to Diagnosing Prostate CancerAshley E. RossAlon LazarovichAaron S. DahmenAbhinav SidanaJack MillotJonathan E. ShoagHangcheng FuJohn EiflerThe diagnosis of prostate cancer (PCa) has changed substantially over the last decade. An increased understanding of disease behavior has led to the development of more specific biomarkers that may limit the numbers of prostate biopsies performed as well as the overdiagnosis of low-grade disease. We have concurrently seen the refinement of imaging techniques such as multiparametric magnetic resonance imaging (mpMRI), which can also limit overdiagnosis and aid in the discovery of clinically significant disease. We now have various options for performing ultrasound-guided biopsies, including transperineal and transrectal approaches. In this article, we gather perspectives on contemporary pathways toward the diagnosis of PCa from experts practicing in large urology practice groups and academia.Prostatic neoplasmsBiomarkersMagnetic resonance imaging (MRI)
Volume 2, Number 1Review ArticlesHyperprolactinemia and Erectile DysfunctionCase ReviewJacob RajferScott I ZeitlinErectile dysfunctionImpotenceHyperprolactinemiaPituitary neoplasmsProlactinMagnetic resonance imaging (MRI)