Volume 6, Supplement 9SupplementComparison of Clinical Trials With Finasteride and DutasterideJ Curtis NickelBenign prostatic hyperplasiaMedical therapyFinasterideDutasterideDihydrotestosterone5-reductase
Volume 7, Supplement 7Review ArticlesFactors in Predicting Failure With Medical Therapy for BPHSteven A KaplanBenign prostatic hyperplasiaMedical therapyBlockers5-reductase inhibitorsPredictors of treatment failureClinical trial results
Volume 10, Number 1Review ArticlesCurrent Medical Therapies for Men With Lower Urinary Tract Symptoms and Benign Prostatic Hyperplasia: Achievements and LimitationsTreatment UpdateClaus G RoehrbornOver the last 20 years, our understanding of the pathophysiology and symptomatology of men with lower urinary tract symptoms (LUTS) has become increasingly more sophisticated. With this increase in sophistication, our utilization of various medical therapies, either alone or in combination, has also increased the understanding of the roles of individual medications, combinations of medications, and the benefits of different types of intervention. The rapid decline of the use of transurethral resection of the prostate (TURP) and other surgical procedures for benign prostatic hyperplasia (BPH) in the 1990s is due in part to the introduction of medical therapy. This article reviews the current state of medical therapy for men with LUTS and highlights its promises and its current limitations. [Rev Urol. 2008;10(1):14-25]Benign prostatic hyperplasiaMedical therapy5-Alpha-reductase inhibitorsLower urinary tract symptomsAlpha-adrenergic receptor blockers
Volume 11, Number 4Review ArticlesDefining Efficacy in the Treatment of Overactive Bladder SyndromeManagement UpdateVictor W NittiSagar ShahPatients seek treatment for overactive bladder syndrome (OAB) due to poor quality of life, and perceived improvement in quality of life (QOL) from medical therapy is multifactorial. Many feel that efficacy/success of medical therapy for OAB should not be linked to improvements in 1 or 2 endpoints, but instead should be linked to patient expectation and QOL improvement. Ideally, once patient-centered goals are defined, outcomes should be correlated with relief of symptom(s), patient satisfaction, and goal attainment expectations as a result of treatment.[Rev Urol. 2009;11(4):196-202 doi: 10.3909/riu0480]© 2009 MedReviews®, LLCMedical therapyOveractive bladder syndromePatient-centered treatment
Volume 21, Number 4Review ArticlesLong-term Consequences of Medical Therapy for Benign Prostatic HyperplasiaManagement UpdateEric M BortnickVannita Simma-ChiangSteven A KaplanBenign prostatic hyperplasia (BPH) is a common disease in men. Although transurethral resection of the prostate (TURP) is the gold standard therapy for treatment of BPH and associated lower urinary tract symptoms (LUTS), many patients choose to avoid surgery and instead choose medical therapy. Until recently, medical therapy for BPH has been thought to be both safe and effective. However, new studies have shown that some of these medications can have significant neurocognitive, psychiatric, and sexual side effects, including dementia and depression. As most patients taking these medications will continue them for the long term, it is vital for physicians to explain these potential risks to the patient prior to prescribing them for a quality-of-life condition. [Rev Urol. 2019;21(4):154–157] © 2020 MedReviews®, LLCBenign prostatic hyperplasiaMedical therapyDepressionDementia5-Alpha-reductase inhibitorsalpha-blockers