Volume 23, Number 4Coding CornerReimbursement Considerations for Instillation of Medications to Treat Low-Grade Upper Tract Urothelial CarcinomaJonathan RubensteinMark PainterCeleste KirschnerUnlike non–muscle invasive bladder cancer, which can be treated with surgical and intravesical medication administration, upper tract urothelial (renal pelvis and ureter) cancer was historically treated only surgically. If a tumor could not be treated with ureteroscopic or percutaneous surgical control, removal of the kidney and ureter was often the only treatment option. When mitomycin for pyelocalyceal instillation 0.4% gel for low-grade upper urothelial cancer became commercially available, nonsurgical treatment became possible.MitomycinAdministration intravesicalureteral neoplasms