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Randall B Meacham

All articles from this author are listed below.

Volume 15, Number 4 Review Articles

The Use of In Vitro Fertilization in the Management of Male Infertility: What the Urologist Needs to Know

Management Review

Randall B Meacham Sahar M Stephens Daniel M Arnett

Infertility affects approximately 10% to 20% of reproductive-age couples, many of whom may present initially to a urologist. Some couples may be treated medically to increase spontaneous conception rates; however, many will require more aggressive management with in vitro fertilization (IVF) and/or intracytoplasmic sperm injection (ICSI). IVF involves ovarian stimulation, oocyte retrieval, and fertilization outside of the body; ICSI involves injecting one sperm into the oocyte to promote fertilization. Here we provide a brief overview of IVF and ICSI along with a discussion of the risks involved to facilitate the counseling and care of the infertile couple. [Rev Urol. 2013;15(4):154-160 doi: 10.3909/riu0588] © 2014 MedReviews®, LLC

Male infertility In vitro fertilization Intracytoplasmic sperm injection

Volume 17, Number 4 Review Articles

Fertility Preservation Options for Men and Women With Cancer

Management Update

Malgorzata E Skaznik-Wikiel Sara Babcock Gilbert Randall B Meacham Laxmi A Kondapalli

Approximately 0.2% of Americans aged 20 to 39 years are childhood cancer survivors. Advances in cancer detection and therapy have greatly improved survival rates for young cancer patients; however, treatment of childhood cancers can adversely impact reproductive function. Many cancer patients report a strong desire to be informed of existing options for fertility preservation and future reproduction prior to initiation of gonadotoxic cancer therapies, including surgery, chemotherapy, and radiotherapy. This article discusses, in detail, the effects of cancer treatment on fertility in men and women, and outlines both current and experimental methods of fertility preservation among cancer patients. [Rev Urol. 2015;17(4):211-219 doi: 10.3909/riu0666] © 2016 MedReviews®, LLC

Fertility preservation Childhood cancer Sperm cryopreservation Testicular tissue cryopreservation Spermatogonial stem cell cryopreservation Embryo cryopreservation Oocyte cryopreservation Ovarian tissue cryopreservation