Volume 15, Number 4Literature ReviewsPSA Velocity in Risk Stratification of Prostate CancerProstate CancerStacy LoebMarc A Bjurlin[Rev Urol. 2013;15(4):204-206 doi:10.3909/riu0590b] © 2014 MedReviews®, LLC
Volume 18, Number 4Review ArticlesSmoking-related Genitourinary Cancers: A Global Call to Action in Smoking CessationDisease Outcome UpdateMarc A BjurlinJosh GottilebCory HigleyRoman SosnowskiSmoking is a known modifiable risk factor in the development of genitourinary malignancies. Although the association has long been supported by numerous research studies, the impact of smoking cessation on the decreased risk of genitourinary malignancies is less well studied. PubMed databases were searched using the terms smoking, smoking cessation, bladder cancer, kidney cancer, prostate cancer, penile cancer, testicular cancer, their synonyms, and also targeted manual searches to perform a literature review in order to summarize the benefits of cessation on disease progression and patient outcomes including survival and morbidities. Our review yielded substantial evidence highlighting the improved outcomes observed in those diagnosed with bladder, renal, and prostate cancers. The risk of bladder cancer is reduced by up to 60% in those who were able to quit for 25 years and the risk of kidney malignancy was reduced by 50% in those who abstained from smoking for 30 years. A similar trend of reduced risk was observed for prostate cancer with those who quit for more than 10 years, having prostate cancer mortality risks similar to those that never smoked. Although the data were encouraging for bladder, renal, and prostate malignancies, there are comparatively limited data quantifying the benefits of smoking cessation for penile and testicular cancers, highlighting an opportunity for further study. The role of urologists and their impact on their patients’ likelihood to quit smoking shows more than half of urologists never discuss smoking cessation upon diagnosis of a malignancy. Most urologists said they did not provide cessation counseling because they do not believe it would alter their patients’ disease progression. Studies show urologists have more influence at changing their patients’ smoking behaviors than their primary care physicians. The diagnosis of cancer may lead to a teachable moment resulting in increased smoking quit rates. Furthermore, implementing a brief 5-minute clinic counseling session increases quit attempts and quit rates. Diagnosis of genitourinary cancers and the following appointments for treatment provide a unique opportunity for urologists to intervene and affect the progression and outcome of disease. [Rev Urol. 2016;18(4):194-204 doi: 10.3909/riu0729] © 2016 MedReviews®, LLCSmokingRisk reductionSmoking cessationGenitourinary malignancy
Volume 20, Number 1NYU Case of the MonthManagement of Penile CancerMarch 2018Danil V MakarovMarc A Bjurlin[Rev Urol. 2018;20(1):46–48 doi: 10.3909/riu2001NYUCOM] © 2018 MedReviews, LLC®
Volume 20, Number 1NYU Case of the MonthManagement of Recurrent Non–Muscle Invasive Bladder CancerJanuary 2018Marc A Bjurlin[Rev Urol. 2018;20(1):38–40 doi: 10.3909/riu0789] © 2018 MedReviews, LLC®
Volume 20, Number 1Review ArticlesDifferentiating Molecular Risk Assessments for Prostate CancerRisk Assessment ReviewMichael SchulsterMarc A BjurlinBenjamin PressIt is critically important to the evolving goals of prostate biopsy to find clinically significant cancer with lethal potential and avoid detection of indolent disease. Better tests and markers are required for improved detection of clinically significant prostate cancer and avoidance of biopsies in men with indolent disease. Currently, there are myriad alternative prostate cancer risk-assessment tests available derived from serum and urine that are designed to improve the specificity for detection of “significant” prostate cancer. Herein we discuss these tests and their clinical implications. [Rev Urol. 2018;20(1):12–18 doi: 10.3909/riu0787] © 2018 MedReviews, LLC®Prostate cancerScreeningProstate-specific antigenBiomarkersPSA