Volume 13, Number 1Review ArticlesDemystifying the Medical Management of NephrolithiasisManagement UpdateMichael LipkinGlenn M Preminger"Nephrolithiasis is a common problem associated with significant costs to the health care system. Its prevalence continues to increase, particularly in women, which is attributed to changes in diet and lifestyle. The costs associated with the evaluation and management of nephrolithiasis in the United States has been estimated to be $1.83 billion, and, without any intervention, the risk of recurrence is high. This article reviews the management options for nephrolithiasis including a new formulation of potassium citrate, UrocitÆ-K 15 mEq, that allows for dosing flexibility which can lead to improved compliance and tolerability. [Rev Urol. 2011;13(1):34-38 doi: 10.3909/riu0522]"NephrolithiasisStandard metabolic evaluationHypercalcuria