Volume 7, Supplement 7Review ArticlesLonidamine: Basic Science and Rationale for Treatment of Prostatic Proliferative DisordersMichael K BrawerBenign prostatic hyperplasiaMagnetic resonance spectroscopyLonidamineMetabolic targetingGlycolysis
Volume 8, Supplement 1Review ArticlesMagnetic Resonance Imaging and Spectroscopy of Prostate CancerProstate Cancer ImagingPeter R CarrollFergus V CoakelyJohn KurhanewiczMagnetic resonance imaging may improve the staging of prostate cancer compared with clinical evaluation alone, computerized tomography, or transrectal ultrasound, and it allows simultaneous and detailed evaluation of prostatic, periprostatic, and pelvic anatomy. Endorectal magnetic resonance imaging and magnetic resonance spectroscopic imaging (endoMRI/MRSI) allow better visualization of the zonal anatomy of the prostate and better delineation of tumor location, volume, and extent (stage). Metabolic criteria used to identify and localize prostate cancer with endoMRI/MRSI have been standardized, thus improving the accuracy of the examination and limiting interobserver variations in interpretation. Evidence is now emerging that endoMRI/MRSI may also be helpful in assessing response to prostate cancer treatment, most commonly with radiation and/or androgen-deprivation therapy. [Rev Urol. 2006;8(suppl 1):S4-S10]Prostate cancerMagnetic resonance imagingMagnetic resonance spectroscopyEndorectal MRI