Volume 11, Number 1Case ReviewRenal Involvement by Chronic Myelomonocytic Leukemia Requiring NephroureterectomySamir S TanejaJonathan MelamedOjas D ShahElias S HyamsRaavi GuptaChronic monomyelocytic leukemia (CMML) is a relatively rare clonal hematologic disorder with features of myelodysplastic syndrome and myeloproliferative disease. Renal impairment from CMML is infrequent and can result from both direct (ie, infiltrative) and indirect (eg, vasculitis, infarction) mechanisms. This case report describes a patient with refractory gross hematuria requiring nephroureterectomy with diffuse involvement of the upper tract by CMML and accompanying extramedullary hematopoiesis. Underscored are the need to maintain a broad differential diagnosis for upper tract lesions in the setting of gross hematuria, and the potential need for drastic measures to control upper tract bleeding if conservative measures fail.[Rev Urol. 2009;11(1):33-37]Gross hematuriaSecondary malignancy of kidneyLeukemia
Volume 12, Number 4Case ReviewSpontaneous Rupture of a Renal Artery Aneurysm Presenting as Gross HematuriaShawn EL WasonThomas SchwaabRenal artery aneurysms (RAAs) are localized dilations of the renal artery and/or its branches. They are being found with increasing frequency as a result of unrelated abdominal imaging or on workup for hypertension. They are rarely symptomatic; however, they can be a cause of life-threatening hematuria. Discussed is the case of a previously healthy 46-year-old man presenting with flank pain and gross hematuria. It is imperative for the practicing urologist to be aware of the appropriate evaluation and management of RAAs.[Rev Urol. 2010;12(4):e193-e196 doi: 10.3909/riu0489]© 2010 MedReviews®, LLCRenal artery aneurysmAbdominal aortographyGross hematuria