Volume 17, Number 1Case ReviewAdenocarcinoma of the Urethra With Mucinous FeaturesArthi SatyanarayanLucas ReddAnthony DyerAndrew WrightJonathan WalkerPrimary adenocarcinoma of the female urethra is a rare malignancy. Previous studies hypothesize multiple origins, including periurethral glands or intestinal metaplasia. We report a case of a 60-year-old white woman with adenocarcinoma of the urethra who initially presented with obstructive voiding complaints secondary to a urethral mass. Wide local excision revealed invasive adenocarcinoma of the urethra with mucinous features. There was intestinal metaplasia adjacent to the tumor, as well as separate identification of intestinal metaplasia along the urethra. Ultimately, the patient underwent radical cystectomy with ileal conduit urinary diversion with no evidence of recurrence, indicating the role of early identification and surgical intervention for such cases. [Rev Urol. 2015;17(1):38-41 doi: 10.3909/riu0622] © 2015 MedReviews®, LLCUrethraUrethral adenocarcinomaSkene glandGenital tract tumorRadical cystectomy