Volume 14, Number 1Case ReviewAdult Wilms’ Tumor With a Unique Presentation of High-Grade Fever, Photophobia, and HeadacheJay KrishnanJerome PietrasMarcella NachmannWilms’ tumor is the second most common tumor in children, accounting for 6% to 7% of all childhood tumors. However, in adults, it is a rare occurrence. The true incidence of adult Wilms’ tumor is difficult to ascertain because of its rarity in the adult population. A review of literature demonstrates that fewer than 300 cases have been reported worldwide. Treatment guidelines in adults have not been established, although reported prognosis is worse for adults compared with children because the disease is more advanced in adults at the time of diagnosis. Reported here is a case of adult Wilms’ tumor presenting as high-grade fever and abnormal laboratory values. [ Rev Urol. 2012;14(1/2):31-34 doi: 10.3909/riu0541] © 2012 MedReviews®, LLCWilms’ tumorRenal massOpen radical nephrectomyMultimodal therapy