Editorial Board About Us

Jacob Rajfer

All articles from this author are listed below.

Volume 11, Number 2 Literature Reviews

Erectile Dysfunction

News and Views From the Literature

[Rev Urol. 2009;11(2):116]

Volume 11, Number 1 Literature Reviews

Ejaculation Disorders

News and Views From the Literature

[Rev Urol. 2009;11(1):41]

Volume 12, Number 1 Case Review

Diagnostic and Therapeutic Options for the Management of Ischemic and Nonischemic Priapism

Case Review

Jeffrey Bassett Jacob Rajfer

Priapism is defined as persistent penile erection continuing beyond, or unrelated to, sexual stimulation. Proper diagnosis encompasses at least 2 very different pathophysiologic processes. Ischemic priapism (“low flow”) is a disorder of venous outflow and/or stasis. Nonischemic priapism (“high flow”) is a disorder of arterial flow. We present 2 cases that review each condition. The first case highlights a 32-year-old man with a medical history of sickle cell disease who presented to the emergency department complaining of a persistent, painful erection that had continued for 18 hours. The second case describes a 24-year-old man with no significant medical history who sustained trauma to his pelvis while skateboarding. Although the initial evaluation of both types of priapism is similar, pathophysiology and resulting interventions differ for each, underscoring the importance of proper diagnosis.[Rev Urol. 2010;12(1):56-63 doi: 10.3909/riu0457]

Erectile dysfunction Ischemic priapism Nonischemic priapism Intracorporeal pressure Cavernosal hypoxia Phosphodiesterase type 5 Distal shunts

Volume 15, Number 3 Meeting Reviews

Best of the 2013 AUA Annual Meeting Part II

More Highlights From the 2013 American Urological Association Annual Meeting, May 4-8, 2013, San Diego, CA

Scott I Zeitlin Ellen Shapiro Jacob Rajfer

[Rev Urol. 2013;15(3):118-123 doi: 10.3909/riu2013AUA2] © 2013 MedReviews®, LLC

Febrile urinary tract infection Male infertility Exogenous testosterone therapy MicroTESE Klinefelter’s syndrome Variocele Vasectomy reversal Antibiotic resistance

Volume 18, Number 2 Review Articles

The Role of Estrogen Modulators in Male Hypogonadism and Infertility

Disease State Review

Jesse N Mills Jacob Rajfer Amarnath Rambhatla

Estradiol, normally considered a female hormone, appears to play a significant role in men in a variety of physiologic functions, such as bone metabolism, cardiovascular health, and testicular function. As such, estradiol has been targeted by male reproductive and sexual medicine specialists to help treat conditions such as infertility and hypogonadism. The compounds that modulate estradiol levels in these clinical conditions are referred to as selective estrogen receptor modulators (SERMs) and aromatase inhibitors (AIs). In a certain subset of infertile men, particularly those with hypogonadism, or those who have a low serum testosterone to estradiol ratio, there is some evidence suggesting that SERMs and AIs can reverse the low serum testosterone levels or the testosterone to estradiol imbalance and occasionally improve any associated infertile or subfertile state. This review focuses on the role these SERMs and AIs play in the aforementioned reproductive conditions. [Rev Urol. 2016;18(2):66-72 doi: 10.3909/riu0711] © 2016 MedReviews®, LLC

Selective estrogen receptor modulator Aromatase inhibitor Male infertility Hypogonadism